Friday, March 1, 2013

Evernote for iOS updated with new PDF viewer and Snippets for iPad

DNP Evernote for iOS updated with a new PDF viewer and Snippets for iPad

Earlier today, Evernote pulled the trigger on version 5.2 of its iOS application. The newfangled software introduces an updated PDF viewer that adds multi-page viewing, screen rotation lock, two-page display within landscape mode and the ability to search text inside a file. Other new app features include plain text note formatting and offline Notebook support for business accounts. iPad users now have access to Snippets list viewing, Business Notebook syncing and the ability to download third-party Trunk software from within the app. If your device is running iOS 5.0 or later and you'd like to sample this smorgasbord of new features, head on over to the App Store or visit the source link below.

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Source: iTunes, The Evernote Blog

Source: http://www.engadget.com/2013/02/28/evernote-ios-updated-pdf-viewer-snippets/

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Big spending cuts mark tea party success, and risk

WASHINGTON (AP) -- The pending $85 billion in federal spending cuts would seem like a tea partyer's dream. Why, then, are tea party activists and other conservatives so wary on the eve of the big reductions, which Congress and the White House seem unable or unwilling to stop?

It's because even ardent cost-cutters see the so-called "sequester" as a ham-handed and unpredictable way to reduce federal spending. While a few tea party activists are claiming all-out victory, others are keeping their distance, calling the across-the-board cuts the least-bad of several unpleasant options.

"I think it's a crazy idea," said Sen. Marco Rubio, R-Fla., a tea party favorite. "The only thing crazier than sequester is to walk away from the cuts that it guarantees."

Rubio's remarks reflect Republicans' nervousness about how the public might react to the domestic and military spending cuts scheduled to begin Friday.

But in many ways, the sequester marks the tea party movement's maturation into a virtually mainstream role in the Republican Party. Cutting the Pentagon's budget once was unthinkable for most Republican lawmakers. But now it is trumped by the drive to keep taxes down while reducing costs wherever possible.

Congressional Democrats and Republicans agreed to the sequester in 2011 only as a consequence so unpalatable that it would goad them into finding a deficit-reduction compromise. The compromise never materialized, however, and now the nation is about to swallow what lawmakers once called a "poison pill" of their own making.

Republicans fear a possible backlash against program cuts and furloughs of government workers and contractors, especially at military bases. They also worry that the cuts will have an economic domino effect, eliminating thousands of private-sector jobs and possibly pushing the nation back into recession.

If that happens, and if voters decide Republicans are chiefly to blame, then the tea party movement could further divide an already roiling GOP.

President Barack Obama and other Democrats say Republican intransigence on tax increases is the sequester's main cause. And public polls indicate Americans are more inclined to fault the GOP if things go badly, although some Republicans believe they can change that.

For now, the approaching cuts are testament to the power of anti-tax sentiment ? and, to a less proven degree, anti-spending sentiment ? in the Republican Party. The tea party movement is strongly associated with these sentiments. But it certainly can't take all the credit.

Long before the tea party's birth in 2009, anti-tax activists such as Grover Norquist were pushing the Republican Party to take inviolable stands against new taxes, even as the deficit soared and the federal tax burden approached historic lows.

Obama won re-election after calling for new taxes on the wealthy. He achieved some of them in January. But Republican lawmakers now say "no more," contributing to the sequester impasse.

The tea party has lost much of its exotic flavor that was punctuated by noisy rallies with costumed activists in 2009 and 2010. Its influence, however, appears larger now. "It has melted into the GOP base," said John J. Pitney, Jr., a former Republican staffer who teaches political science at Claremont McKenna College in California. "Anti-tax voters make up a large share of the vote in GOP primaries," he said, "so Republican lawmakers support tax increases at their peril."

But Republicans could face another kind of peril, Pitney said, if the sequester lasts for months and begins to erode "visible, popular programs."

Duke University political scientist David Rohde said the tea party has become "the populist conservative faction of the Republican Party." It drew well-deserved credit for fueling the Republicans' big congressional and gubernatorial wins in 2010, he said, even though some tea party-backed Senate nominees lost key races.

The movement's future, Rohde said, depends on whether tea party activism is seen as helping or hurting Republican candidates in 2014 and beyond. Fallout from the sequester could play a big role in those elections.

Sen. Lindsey Graham of South Carolina is typical of Republican lawmakers who grudgingly accept the sequester and worry that tea party ideals can go too far.

"I believe that the cuts in defense are ill-conceived and will do a lot of damage," said Graham, whose state includes several military installations. "Some of these tea party folks don't mind losing their bases; others will."

The tea party drive to reduce federal spending at almost every level is potent in GOP circles. Rep. Jack Kingston of Georgia, eyeing a Senate race that will draw several hard-right Republican rivals, says the sequester appears inevitable, but it will extract an economic and political price.

Referring to military bases in his Savannah-based district, Kingston said, "my people will take it on the chin." But in constituent feedback about the sequester, he said, "the overwhelming number of people are saying, "Let it happen." They want to see that we are serious about cutting spending."

Even some tea party leaders say the movement's take-no-prisoners approach has its costs.

"Our brand is tarnished, but that's what happens when you get beat up," said Sal Russo, a founder of the California-based Tea Party Express. "It's not the brand" that counts, he said, "it's the ideas."

In the long run, Russo said, the benefits of reducing deficit spending will overshadow any short-term hits to the economy this year. If that happens, he said, the tea party's status will rise in the Republican Party and the nation at large.

The movement "is quite alive and well," he said.

But some question the tea party's willingness to embrace domestic and military cuts that don't touch the greatest causes of deficit spending: the popular but costly "entitlement" programs of Medicare, Medicaid and Social Security.

"They're amputating the wrong limb," said Rutgers University political scientist Ross Baker. If the tea party movement is to achieve its goal of undoing the government's borrowing habits, he said, it must prove it can blaze a political path to reductions in entitlement spending.

Source: http://news.yahoo.com/big-spending-cuts-mark-tea-195151299.html

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Giuliana Rancic Puts Marriage Before Baby -- And That's Okay!

Giuliana Rancic and her husband Bill worked really hard to have a baby. After she underwent a double lumpectomy and double mastectomy and failed to conceive on her own, the couple decided to bring in a surrogate and have their child through a gestational carrier. The plan worked, and the Rancics welcomed baby Edward Duke into the world in late August.

Source: http://www.ivillage.com/giuliana-rancic-puts-marriage-baby-and-thats-okay/1-a-524561?dst=iv%3AiVillage%3Agiuliana-rancic-puts-marriage-baby-and-thats-okay-524561

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Latest ATM technology to be in focus at Airport Show-2013 - AME Info

The Middle East airlines are expected to experience the highest growth in passenger traffic at 5.8% per annum through to the year 2025, compared to the world average of 4.6%.

The total aircraft movements to/from and within the Middle East region are estimated to increase to 2,346,000 in 2025 at an average annual growth rate of 7.6%. While aircraft movements in the UAE witnessed 6.7% growth in 2012, there has been a 16.2% growth in the fleet of UAE-registered airlines/operators in the past 10 years.

According to industry experts, over 50% of Middle East's airline traffic and over 65% of business aviation traffic is concentrated in the GCC region.

The General Civil Aviation Authority's (GCAA) strategic plan notes that increasing demand for air travel will continue to challenge the efficiencies of the air traffic management system.

While the hub-and-spoke system will remain largely the same as today for major airline operations, the demand for more point-to-point service will create new markets and spur increases in low-cost carriers, air taxi operations, and on-demand services.

Additionally, the emergence of VLJ's (Very Large Jets) is expected to create new markets in the general and business aviation sectors for personal, air taxi, and point-to-point passenger operations. Many airports will thus experience significant increases in unscheduled traffic, while many airports that support scheduled air carrier traffic are forecast to grow and experience congestion or delays, if efforts to increase their capacity fall short. As a result, additional airspace flexibility will be necessary to accommodate not only the increasing growth, but also the increasing air traffic complexity.

Nearly 50% of the GCC airspace has some form of restriction, much of it military, denying commercial aircraft the use of the most efficient flight corridors, creating unnecessary added costs for airlines.

Aircraft have to follow a pre-determined route regardless of wind conditions, leading to unnecessary fuel consumption, excess carbon emissions, longer flight times, increased noise impact, flight delays and air traffic congestion. More than US$700 million is estimated to be the volume of investments in regional ATM upgrades, while equally significant investments in this segment are in the pipeline.

The UAE airspace is among the most important airspaces in the world due to its strategic location, in essence a link between East and West. The UAE has a total of 120,000 square kilometers of airspace, with 35 international air corridors.

GCAA and Airbus ProSky have recently signed an agreement for the UAE Airspace Enhancement programme, beginning this year. The UAE Flight Information Region (FIR) witnessed a total of 741,450 aircraft movements in 2012.

Saif Mohammed Al Suwaidi, Director General of General Civil Aviation Authority (GCAA), said: "It is due to the rapid expansion of our national operators and the other regional carriers, with the limitations and the small size of the UAE airspace, and in addition to the overburdening regional constrains and restrictions in areas beyond the control of the UAE, we have delays and bottlenecks in the UAE FIR."

Mohammed Ahli, Director General of Dubai Civil Aviation Authority (DCAA), said: "In the past, most aviation congestion occurred on the ground. Today the biggest strategic challenge to growth of aviation is in the air. The development of two aerospaces is also under way. One of these will be within the GCC and the other will serve as an international aerospace."

Daniyal Qureshi, Show Director, The Airport Show, said: "Better management of the airspace is among the serious challenges that the aviation authorities face in their growth aspirations. Airspace reform in the region is overdue and requires a huge commitment from all the governments and stakeholders like ANSPs, airports and airlines. Current ATM systems are not able to keep up with demand and huge investments are needed."

The latest ATM solutions and systems will be on display at the Airport Show in Dubai from May 6 to 8. The 13th Airport Show will feature exhibitors specialising in ATC Towers, Mobile Control Towers, Communications, Data Processing Systems, Consoles, Enclosures, Landing Systems, Navigational Aids and Fleet Management.

Tony Tyler, CEO and Director General of the International Air Transport Association (IATA), said: "The Middle East region must avoid the inefficiencies that we see in Europe. In the Gulf, ATM delays are already nearing crisis levels. It would be a shame if the potential of the investment in ground infrastructure was held back by a lack of progress in the air. If congestion problems are allowed to grow they can quickly turn unmanageable. And the bigger they get, the more difficult the solution."

According to an Oxford Economics study, the Middle East region has 1029 aircraft in service, operated by 65 airlines from 70 commercial airports. The GCC region has 36 airports, including eight in the UAE. Emirates Airlines, Etihad Airways and Qatar Airways lead the pack and account for the vast majority of the new aircrafts ordered. Over the next five years, they are forecasted to increase capacity at more than 15% per annum, according to a study, Mastering the Challenges of The Middle East Aviation System, by Booz & Co. This means the GCC skies will get even more crowded.

According to GCAA, UAE FIR will have 895,468 flight movements in 2015, over 1.13 million flight movements by 2020 and 1.63 million flight movements by 2030. Capacity improvement of the UAE airspace was highlighted in a stakeholder study carried out by the GCAA, which says that growth in scheduled and general aviation aircraft is expected to increase point-to-point and direct routings.

According to Air Transport Action Group's recent study, Revolutionising Air Traffic Management, with 13 FIRs to manage, the Middle East ANSPs control more than 1.7 million movements between 15 international airports, as well as 700,000 movements between 45 domestic airports every year. The International Civil Aviation Organisation (ICAO) and Civil Air Navigation Services Organisation (CANSO) recommended that ANSPs modernize their infrastructure by investing in digital communications, surveillance and navigation (CNS) technology.

Salim Al-Aufi, CEO of Oman's Public Authority for Civil Aviation, said: "One of our main challenges is that our airspace is very congested. Today, we have five airspace sectors. Next year, we are going to open up two additional sectors. There will be a lot of demand for airspace and we are considering many options to help solve the issue."

In Bahrain, the aircraft movements recorded a 12% growth between 2003 and 2012, while it is expected to be around 11% between 2013 and 2022.

Fareed Al Alawi, Head of Air Traffic Operations at Bahrain Civil Aviation Affairs, said: "A major obstacle to producing more en-route capacity is that the Middle East airspace has not yet been optimized. Civil-Military cooperation has become very important in the current aviation environment because of the continuous rapid growth in civil air traffic. Failure to add additional routes structures, particularly within the Bahrain FIR, will result in severe limitation in the ability to increase air traffic capacity."

The scenario is no different in other states like Saudi Arabia and Kuwait given the high growth being recorded in air travel volumes and expansion of airlines. Saudi Arabia is projected to have a combined future capacity of 140 million passengers each year, up from 54.5 million passengers in 2011. In Kuwait, there were 85,567 aircraft movements in 2012.

Source: http://www.ameinfo.com/atm-technology-focus-airport-show-2013-331516

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Samsung re-starts copier, announces Passbook for Android

Samsung announced their new Samsung Wallet today. The video above is from frAndroid, and here's Simon Sage's background on it from Android Central:

Samsung has announced a new API for developers to help manage event tickets, boarding passes, memberships, and coupons. Samsung Wallet will be a new application which brings all of these types of content into one place. Time and location-based push notifications will help users get a hold of the ticketing information.

If that sounds -- and looks -- familiar, it's because Apple already announced it back in June of 2012 as Passbook.

Samsung re-starts copier, announces Passbook for Android

It's not the first time Samsung's copied an Apple product, it's probably not even the hundred-and-first, though given their bolder, more authentic releases over the last year, it did seem to be something they were growing out of. Apple isn't adverse to copying features from Android either, though historically they haven't been as consistent or blatant about it.

Like with black slab designs I'm pretty much over any obsession with who's copying who, but I do think this smacks of laziness and a lack of pride.

I'm happy for Samsung users that they'll get to enjoy a feature that's been nifty, if limited so far, on iOS 6. But it shows Samsung really doesn't give a shit. Passbook is certainly not the only way to tackle a digital wallet, and it may not even be the best way. By relentlessly copying, Samsung isn't moving the technology forward. They're not raising the bar. They're not making a wallet interface and experience so good anyone is begging for Apple to copy them.

I own a Nexus 4 and Nexus 7, which have LG and Asus designs, and Google software, and I'm currently waiting for an HTC One (love HTC). I have little interest in Samsung products, and it's mostly because of stuff like this. And I want to have interest in Samsung. I want a better Samsung.

Obviously Samsung's making all the money in Android these days, and their upcoming Galaxy S4 will no doubt be an unprecedented hit, so they probably don't care.

But they really, really should.

Source: frAndroid via Android Central



Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/YoBaSGLG7Jg/story01.htm

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Family thank neighbours for help during Taunton garden fire (From ...

Family thank neighbours for help during Taunton garden fire

A FAMILY has thanked quick-thinking neighbours who put their lives on the line to help stop a raging fire reaching their house.

Vicki Moore, 28 and her husband Nick, 43, were watching television at their home in Cheddon Road, Taunton, on Friday (February 22) night when they heard two explosions.

Mr Moore investigated outside and when he opened the back door he was greeted with flames heading towards the house.

Mrs Moore said: ?My husband said ?get everybody out? as he tried to put the fire out.

?Three neighbours nearby helped him and it is just a massive thank you to them for ringing the fire service and looking after my husband.

?It was all a bit of a scare.?

Mrs Moore and her three children, Kaden, nine, Leon, eight, and Bethany, five, left through the front of the house to safety.

As Mr Moore tackled the flames at the back of the property he almost collapsed due to smoke inhalation but one of the neighbours arrived just in time to pull him away before taking over the hosepipe to tackle the flames.

Mr Moore was treated by ambulance crews and the family, who have lived at the house since 2008, say they are in the process of clearing up all the rubble the fire has left in their garden.

A Devon and Somerset Fire spokesman said they sent one fire engine and four firefighters to the scene and believe the fire started in a pile of rubbish at the back of the two-storey property.

Is community spirit still alive? Would you help your neighbours out? Let us know.

Source: http://www.somersetcountygazette.co.uk/news/taunton_news/10254326.Family_thank_neighbours_for_help_during_Taunton_garden_fire/?ref=rss

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Lipid nanoparticles are ideal for delivering genes and drugs, researchers show

Feb. 28, 2013 ? At the Faculty of Pharmacy of the Basque Public University (UPV/EHU) the Pharmacokinetics, Nanotechnology and Gene Therapy research team is using nanotechnology to develop new formulations that can be applied to drugs and gene therapy. Specifically, they are using nanoparticles to design systems for delivering genes and drugs; this helps to get the genes and drugs to the point of action so that they can produce the desired effect.

The research team has shown that lipid nanoparticles, which they have been working on for several years, are ideal for acting as vectors in gene therapy. Gene therapy is a highly promising alternative for diseases that so far have no effective treatment. It consists of delivering a nucleic acid, for example, a therapeutic gene, to modulate the expression of a protein that is found to be altered in a specific disease, thus reversing the biological disorder.

The main obstacle is that the genetic material cannot be formulated in conventional pharmaceutical ways, because it becomes degraded within the organism and cannot perform its function. To overcome this obstacle, viral vectors are normally used and they are able to deliver the therapeutic gene to the cells in which it has to act. However, as Dr Alicia Rodriguez explains, "viral vectors have a great drawback because they have a great potential to develop tumours. That is why there is a lot of interest in developing non-viral vectors, like vectors based on lipid nanoparticles. "

"In this respect," adds Dr Rodriguez, "we have for several years been working to develop formulations for treating degenerative retina diseases, diseases for which there is currently no effective curative or palliative treatment and which causes blindness in the patients who in many cases are very young people. "The research they have done has borne fruit already, and they have in fact managed to develop a vector capable of making a protein express itself in the eyes of rats after ocular delivery. The work has produced two patents and various papers published in top scientific journals, like Human Gene Therapy.

Aim: to improve drug absorption

Another application of lipid nanoparticles is to develop new formulations to deliver drugs that are not particularly soluble or which are difficult to absorb. Dr Rodriguez explained the problem with these drugs:"40% of the new pharmacologically active molecules are reckoned to be insoluble or not very soluble in water; that prevents many of these potentially active molecules from ever reaching the clinic because of the problems involved in developing a safe, effective formulation. "

The Faculty of Pharmacy's research team has shown that the strategy of encapsulating drugs of this type in lipid nanoparticles is effective:"They are spheres made of lipids and they have very small particles which encase the drug. That way, the absorption of the drug given orally can be increased," points out Dr Rodriguez.

Part of the research was done in collaboration with the research team led by Dr V?ronique Pr?at, of the Catholic University of Louvain in Belgium. There they studied the capacity of the nanoparticles to pass through the intestinal barrier and therefore increase the permeability of the drug. The results of this work have been published in the Journal of Controlled Release, a leading journal within the specialty.

Furthermore, while considerable advances have been made in both areas (vectors for gene therapy and improvement in insoluble drug absorption), the researchers in the Pharmacokinetics, Nanotechnology and Gene Therapy team are working in a third area linked to hepatitis C in which they also hope to achieve positive results.

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The above story is reprinted from materials provided by Elhuyar Fundazioa.

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/bk8zSW-4U9I/130228080248.htm

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